德國的研究團隊利用大鼠的動物實驗發現一個非侵入性的幹細胞療法,能治療帕金森氏症.將間葉幹細胞從鼻腔打入,讓細胞移至大腦中,釋放多巴胺的神經傳導物質,改善運動神經功能.
這項動物實驗證實能改善高達68%的帕金森氏症老鼠的運動神經功能,並且由鼻腔進到腦中的幹細胞能存活六個月之久
鼻腔運送(intranasal delivery)的幹細胞治療法能避免幹細胞移植手術所引起的創傷和發炎現象,並可不斷補充所需的幹細胞,因此更為安全和有效.此項發現已刊登在回春研究(Rejuvenation Research)的期刊
Non invasive Parkinson's treatment 'reduces symptoms'
Healthcare News 09/02/2011
A non-invasive method of delivering stem cells to the brain successfully increased dopamine levels in rats, lessening Parkinson's symptoms, a study showed.
Non-invasive delivery of stem cells to the brain could dramatically improve the symptoms of Parkinson's disease, a study has found.
Research published in journal Rejuvenation Research delivered mesenchymal stem cells (MSCs) to the brains of rats through the nose and successfully reversed the dopamine deficiency seen in the disease.
Levels of dopamine were significantly higher in the areas of the brain which had undergone the treatment and motor functions were seen to improve by up to 68 per cent.
This comes after one expert said that there are no known drugs or lifestyle changes that can prevent the onset of Parkinson's.
Dr Kieran Breen, director of research at Parkinson's UK said that some people develop the condition due to a combination of genetics, lifestyle and environment.
"Parkinson's is a condition that probably takes many years to develop. And as we age our bodies are less resilient - cuts and bruises take longer to heal, and we are at greater risk of all kinds of health issues - cancer, heart problems [and] stroke," he said.
http://www.barchester.com/Healthcare-News/Non-invasive-Parkinson's-treatment-'reduces-symptoms'/376/4117
